Seth Guilbeau, MD
Dr. Seth Guilbeau is a urologist practicing in Lafayette, Louisiana, as part of Southern Urology, a large multidisciplinary group of approximately 15 urologists who collectively provide specialized care across a broad range of urologic conditions. Having recently begun his career in practice, Dr. Guilbeau focuses on advanced treatments including robotic surgery, stone disease management, benign prostatic hyperplasia (BPH) surgery, and therapies for overactive bladder. Robotic-assisted procedures are a particular area of interest for him, allowing him to provide precise, minimally invasive surgical care. He is also committed to expanding access to third-line therapies for overactive bladder, an area he believes has historically been underserved in his region.
Dr. Guilbeau earned his medical degree from LSU Health Sciences Center in New Orleans in May 2020. He then completed his urology residency at the University of Tennessee Medical Center in Knoxville through the Graduate School of Medicine, where he trained from July 2020 through June 2025. Now practicing in Lafayette, he is affiliated with both Ochsner Lafayette General Hospital and Our Lady of Lourdes, where he treats patients with a wide range of urologic conditions. His clinical approach combines advanced surgical techniques with patient-centered care, ensuring individuals receive effective treatment and support throughout their care journey.
His decision to pursue medicine was deeply personal. Dr. Guilbeau’s brother was diagnosed with Friedreich’s ataxia, a rare neurological disorder similar in some ways to ALS, which inspired him to enter the field so he could help others on a more personal level. Today, he finds fulfillment in the immediate impact his work can have—especially in a surgical specialty where procedures often provide rapid relief and improved quality of life for patients. Looking ahead, Dr. Guilbeau hopes to continue serving as a dedicated physician in the Lafayette community, building a long-term career caring for the people of Acadiana and contributing to the health and well-being of the region he proudly calls home.
• LSU Health Sciences Center in New Orleans
• University of Tennessee Medical Center in Knoxville
• American Urologic Association
• American Medical Association
• Alpha Omega Alpha
• Gold Humanism Honor Society
Areas of Specialization/Expertise
- Robotic Surgery
- Stone Disease
- BPH Surgery
- Overactive Bladder
What do you enjoy most about practicing medicine?
I think it's really the immediate gratification that I get from a lot of patients after doing their procedures, and knowing that I've been able to help them, sometimes even in a small way, almost immediately. I feel like a lot of times in some areas of medicine, you're kind of just prescribing medicine and hoping things work, but with a surgical field, you have more of that immediate gratification and really feel like you've put your hands on the patient and played a major role in their health and recovery.