Nikolaos Zacharias, MD, FACOG

OB-GYN
Director, Clinical Professor
University of Houston College of Medicine
Houston, TX 77401

Dr. Nikolaos Zacharias, MD, FACOG, is a board-certified Maternal-Fetal Medicine specialist and Clinical Professor of Obstetrics and Maternal-Fetal Medicine at the University of Houston College of Medicine (Tilman J. Fertitta Family College of Medicine). He is recognized for his expertise in high-risk pregnancy management, prenatal diagnosis, and perinatal complication prevention, combining clinical excellence with a strong commitment to patient safety and advancing maternal and fetal health.

He serves as Director of Maternal-Fetal Medicine at Saint Joseph Medical Center (HSA) in Houston, Texas, and practices through Pediatrix Medical Group, a division of Mednax, Inc. Dr. Zacharias provides care across multiple hospital affiliations, including Methodist Health System, St. Joseph Hospital, and Women’s Hospital of Texas. In addition to delivering expert clinical care, he leads resident training and perinatal education programs through Obstetrix Medical Group of Houston, ensuring the development of the next generation of healthcare professionals.

Dr. Zacharias earned his Doctor of Medicine (MD) from Ethnikon kai Kapodistriakon Panepistimion Athinon (National and Kapodistrian University of Athens, Greece) and completed an OB/GYN residency in Women’s Health at Baylor College of Medicine. He subsequently completed a Maternal-Fetal Medicine fellowship in Perinatology at The University of Texas Medical Branch at Galveston and pursued a Masters in Medical Science (MMSc) in Medical Research Design at UTMB, completing all coursework with distinction. Fluent in Greek and French, he has contributed to the field through publications such as Perinatal Mortality in UpToDate, and remains dedicated to advancing prenatal sonography, maternal-fetal research, and excellence in patient care across hospital and academic settings.

• Ethnikon kai Kapodistriakon Panepistimion Athinon - MD

• Biomedical Investigators
• GCP for Clinical Trials with Investigational Drugs and Medical Devices (U.S. FDA Focus)
• Pediatrix Clinical Research Policies (To be completed by Pediatrix employees only)
• Board Certified Subspecialist in Maternal-Fetal Medicine
• Board certified maternal-fetal medicine expert
• Board Certified Obstetrician Gynecologist

• American College of Obstetricians and Gynecologists
• Texas Medical Association
• Society for Maternal-Fetal Medicine
• American Institute of Ultrasound in Medicine
• International Society of Ultrasound in Obstetrics and Gynecology

Dr. Zacharias has published on perinatal mortality, including an article in UpToDate on June 1, 2009.

Areas of Specialization/Expertise

  • Pre-natal Ultrasound
  • High risk obstetrics
  • Maternal/Fetal Monitoring
Q

What do you enjoy most about practicing medicine?

What I enjoy most about practicing medicine is the opportunity to shape the health of the next generation. Being able to guide patients through critical stages of their lives, promote wellness, and positively impact both mothers and children is deeply rewarding. It is incredibly fulfilling to combine clinical expertise with compassion, knowing that the care I provide contributes not only to immediate health outcomes but also to long-term well-being.

Locations

University of Houston College of Medicine

Houston, TX 77401

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