Marc Difronzo, PA-C
Marc Difronzo, PA-C, is a highly skilled Physician Assistant at Koniver Wellness in Charleston, South Carolina, where he brings a mission-driven, precision-focused approach to patient care. A former Special Operations veteran, he transitioned into medicine with a commitment to disciplined practice, excellence, and service. Marc earned his Master’s degree in Physician Assistant Studies from the University of North Carolina at Chapel Hill and a Bachelor’s degree in Kinesiology and Exercise Science from the College of Charleston, building a strong academic foundation for his clinical expertise.
Marc specializes in regenerative medicine, orthobiologics, peptide therapy, hormone replacement therapy, functional medicine, and performance medicine. He integrates traditional clinical standards with advanced, evidence-based therapeutic modalities to help patients optimize longevity, vitality, and overall performance. His philosophy centers on personalized, outcome-driven care—empowering individuals to perform at their highest physical and metabolic potential while addressing root-cause contributors to health.
Throughout his career, Marc has held key leadership and educational roles, including Director of Medical Operations at QC Kinetix and instructor with Experience Anatomy. Earlier, he served more than a decade in the Army National Guard as a Company Commander, further shaping his leadership style, resilience, and commitment to service. Today, Marc continues to advance innovative medical practice while providing compassionate, high-impact care to patients seeking cutting-edge solutions for health, wellness, and performance.
• The University of North Carolina at Chapel Hill - PA
• College of Charleston - B.Kin.
• Certified Physician Assistant
• American Academy of Physician Associates
Areas of Specialization/Expertise
- Functional Medicine
- Performance Medicine
- Orthobiologics
- Peptide Therapy
- Longevity & Preventive Medicine
What do you enjoy most about practicing medicine?
What I enjoy most about practicing medicine is helping others feel better. There is a profound sense of fulfillment in alleviating pain, improving health, and supporting patients through their medical journeys. Being able to make a positive impact on someone’s life while combining my knowledge, skills, and compassion is what drives me every day to provide the highest standard of care.